Assessment of increasing intravenous adenosine dose in fractional flow reserve
نویسندگان
چکیده
منابع مشابه
Assessment of increasing intravenous adenosine dose in fractional flow reserve
BACKGROUND Effects of increased adenosine dose in the assessment of fractional flow reserve (FFR) were studied in relation to FFR results, hemodynamic effects and patient discomfort. FFR require maximal hyperemia mediated by adenosine. Standard dose is 140 μg/kg/min administrated intravenously. Higher doses are commonly used in clinical practice, but an extensive comparison between standard int...
متن کاملComparison of intracoronary versus intravenous administration of adenosine for measurement of coronary fractional flow reserve.
BACKGROUND Measurement of fractional flow reserve (FFR) constitutes the current gold standard to evaluate the hemodynamic significance of coronary stenoses. Limited data validate the intracoronary application of adenosine against standard intravenous infusion. We systematically compared FFR measurements during intracoronary and intravenous application of adenosine about agreement and reproducib...
متن کاملComprehensive assessment of coronary fractional flow reserve
Fractional flow reserve (FFR) is considered nowadays as the gold standard for invasive assessment of physiologic stenosis significance and an indispensable tool for decision-making in coronary revascularization. Robust studies have shown that FFR is more effective in accurately identifying which lesions should be stented, and revascularization guided by FFR improves the outcome of coronary arte...
متن کاملComparison of effectiveness of high-dose intracoronary adenosine versus intravenous administration on the assessment of fractional flow reserve in patients with coronary heart disease.
Intravenous adenosine is considered the drug of choice to obtain maximum hyperemia in the measurement of the fractional flow reserve (FFR). However, comparative studies performed between intravenous and intracoronary administration have not used high doses of intracoronary adenosine. The present study compared the efficacy and safety of high doses of intracoronary adenosine to intravenous admin...
متن کاملIntracoronary electrocardiogram ST segment shift evaluation during intravenous adenosine infusion: a comparison with fractional flow reserve.
BACKGROUND By measuring the pressure decline caused by coronary narrowing, fractional flow reserve (FFR) is an index of the physiological significance of a vessel stenosis. Intracoronary electrocardiogram (IC-ECG) recording from an angioplasty guidewire is more sensitive than standard ECG in detecting regional myocardial ischemia. The aim of the study was to assess if unipolar IC-ECG ST segment...
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ژورنال
عنوان ژورنال: BMC Cardiovascular Disorders
سال: 2017
ISSN: 1471-2261
DOI: 10.1186/s12872-016-0463-4